Saturday, 23 November 2013

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How to limit the microbial attack by limiting the use of antibiotics.


How to limit the microbial attack by limiting  the use of antibiotics

Are you using or you are habituated of too much antibiotic ,well then think again next time when you get a small infection and you are using antibiotics.It's kind of helping the microbes to become more powerful 



There is a need to develop a new approach to fight various infectious disease which are becoming resistant with advent of time.There are many reports coming of both from developed as well as developing country regarding growing number of bacterial resistance.One such example is Methicillin-resistant Staphylococcus aureus (MRSA) is a bacteria that is resistant to many antibiotics.MRSA causes life-threatening bloodstream infections, pneumonia and surgical site infections. 

S.aureus has evolved several mechanisms to resist the innate immune system.Multidrug resistance among many organisms has become a big challenge to infectious disease management. It is increasingly being reported in bacteria and is often mediated by genetic mobile elements such as plasmids, transposons, and integrons and this process is quite fast as well

Bacterial infections and sepsis are amongst the leading causes of death worldwide. Sepsis is caused by an uncontrolled systemic host response towards an invading pathogen. Due to the engagement of various systems including cell- mediated responses, the coagulation and complement cascades, treatment of sepsis remains challenging. Mortality rate is quite high for patients with septic shock, despite improved health care and antibiotic usage.


The bacterial resistance graph  
Ever growing bacterial resistance




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